Using Runes as Symbols Outside of Norse Spirituality?

What do you think of using runes as symbols, but outside the context of any Norse spirituality? Many people who are not spiritually connected to Norse culture use runes for various purposes, like divination, magic, etc. F’ex, let’s say hypothetically that there are a couple of runes that resonate very strongly with me symbolically (partly because of their own meanings and partly because of what they evoke for me personally and/or how that specific symbol — f’ex, the rune that looks like an arrow — could be interpreted other than as a rune), but I have little interest in Norse spirituality or in runes as a system. Is there any reason I shouldn’t use symbols that work for me, just because they’re outside my own spiritual/cultural frame of reference? What are the potential pitfalls?

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